Authors: Dr Zarir F. Udwadia, MD, FRCP (London), FCCP (USA)
Number of pages: 3
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Overview: Multidrug-resistant (MDRTB) and extensively drugresistant TB (XDR-TB) are demanding conditions to treat and are best managed by a specialist with experience in treating such severe forms of TB. Even in the best hospitals, under optimal conditions, global treatment success rates are in the vicinity of 60% for MDR-TB and 44% for XDR-TB. Errors in treatment amplify resistance and convert MDR strains to XDR-TB and beyond. The 10 principles outlined here maximise the chances of successful outcome.